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Microbiome Analysis Report

Comprehensive gut microbiome profiling powered by shotgun metagenomics and AI-driven analysis.

Patient
Merideth Williams
Patient ID
FF05465495
Sample Date
Feb 10, 2026
Report Date
Feb 17, 2026
Location
Los Angeles, CA
Kit ID
KIT-BB-20260210-5495
Physician
Dr. Sierra Simpson, PhD
Sample Quality
Excellent

Executive Summary

Your overall microbiome health at a glance

0/ 100
Brilliant Score
05.5
Shannon Index
0vs 63 actual
Biological Age
312
Species Detected
0.98
F:B Ratio
0.34
P:B Ratio
Western diet

Health Category Scorecard

Assessment across 12 key health areas connected to your microbiome

Microbiome Diversity

Above Average

Shannon index 5.5, Simpson 0.95 — your microbial ecosystem is rich and well-balanced.

Inflammatory Potential

Average

Moderate inflammatory markers. Bilophila wadsworthia and Ruminococcus gnavus present at low levels.

Metabolic Fitness

High

Strong SCFA production and carbohydrate metabolism driven by multiple butyrate producers.

SCFA Production

High

Excellent short-chain fatty acid production from Faecalibacterium, Anaerostipes, and Anaerobutyricum.

Gut Lining Health

High

Strong gut barrier integrity supported by butyrate producers and mucosal layer maintenance.

Oxalate Metabolism

Low

Limited oxalate-degrading capacity detected. May benefit from dietary oxalate management.

Gas Production Pathways

Average

Normal gas production levels. No significant methane or hydrogen sulfide overproduction.

Ammonia Pathways

Average

Ammonia production within normal range. Adequate urea cycle support from gut microbes.

Salt Pathways

Low

Below average salt metabolism pathways. Consider monitoring sodium intake.

Bile Acid Pathways

Average

Normal bile acid metabolism supporting fat digestion and cholesterol regulation.

TMA Production Pathways

Low

Low TMA production is favorable — reduces cardiovascular risk from TMAO.

Antibiotic Resistance

Not Detected

No antibiotic resistance genes detected in your sample.

Microbial Composition

Phylum-level breakdown of your gut microbiome ecosystem

PhylumBreakdown
Bacteroidota41.06%
30-50%
Bacillota40.07%
30-55%
Verrucomicrobiota3.89%
1-5%
Actinomycetota3.15%
3-15%
Pseudomonadota0.76%
<5%
Thermodesulfobacteriota0.42%
<2%
Other0.65%
<5%

Ratio Analysis

Comparing your Firmicutes:Bacteroidetes and Prevotella:Bacteroides ratios

Ratio Comparison

How your F:B and P:B ratios interact to shape your gut health profile

0.98optimal: 0.8–1.203.0
F:B Ratio

Firmicutes : Bacteroidetes

Optimal
Previous: 1.150.98
0.34Western pattern02.0
P:B Ratio

Prevotella : Bacteroides

Western
Previous: 0.280.34
Combined Analysis

Balanced Gut, Western Diet Signal

Despite a Western-leaning dietary pattern, your gut maintains good balance. This resilience is positive, but shifting toward more plant-based foods could enhance glucose metabolism and reduce inflammation risk.

F:B measures gut balance
P:B reflects diet type
Impacts glucose metabolism
Linked to inflammation patterns

Key Species Identified

Notable bacterial species detected in your sample with clinical relevance

SpeciesAbundanceStatus
Phocaeicola dorei
85 publications
14.33%
Beneficial
Bacteroides ovatus
150 publications
12%
Beneficial
Bifidobacterium longum
420 publications
4.99%
Beneficial
Faecalibacterium prausnitzii
334 publications
3.92%
Beneficial
Lachnospira eligens
65 publications
3.91%
Beneficial
Anaerostipes hadrus
45 publications
2.75%
Beneficial
Anaerobutyricum hallii
38 publications
1.41%
Beneficial
Faecalibacterium longum
28 publications
3.13%
Beneficial

Species Abundance Changes

Track how key species populations have shifted over time

Time Range
Showing data from 6 months before current report
Phocaeicola doreiBeneficial
14.3%
+1.5%
Bacteroides ovatusBeneficial
12.0%
+1.2%
Bifidobacterium longumBeneficial
5.0%
+0.9%
Faecalibacterium prausnitziiBeneficial
3.9%
+0.5%
Anaerostipes hadrusBeneficial
2.8%
+0.5%
Lachnospira eligensBeneficial
3.9%
+0.4%
Bilophila wadsworthiaOpportunistic
0.5%
-0.2%
Escherichia coliOpportunistic
0.0%
-0.0%
6 increasing
2 decreasing
0 stable

Functional Pathways

Metabolic and biochemical pathway activity levels in your microbiome

Butyrate ProductionSCFA Metabolism
Active82

Gut barrier integrity, anti-inflammatory

Propionate SynthesisSCFA Metabolism
Active71

Appetite regulation, gluconeogenesis

Acetate ProductionSCFA Metabolism
Active88

Energy source, cross-feeding substrate

Vitamin B12 SynthesisVitamin Metabolism
Active55

Energy metabolism, neurological function

Folate BiosynthesisVitamin Metabolism
Active68

DNA synthesis, cell division

Tryptophan MetabolismAmino Acid Metabolism
Reduced48

Serotonin/melatonin precursor

GABA ProductionNeurotransmitter
Reduced42

Anxiety regulation, sleep quality

Bile Acid MetabolismLipid Metabolism
Active65

Fat digestion, cholesterol regulation

LPS BiosynthesisImmune Modulation
Reduced35

Low levels favorable — less immune activation

Oxalate DegradationMineral Metabolism
Depleted22

Kidney stone prevention

Symptom Connections

How your microbiome patterns may relate to reported symptoms

Digestive
Occasional Bloating
Immune
Moderate Immune Activation
Metabolic
Oxalate Sensitivity
Gut-Brain
Mild Gut-Brain Axis Imbalance

Personalized Recommendations

Evidence-based actions tailored to your unique microbiome profile

ProbioticHigh

Akkermansia muciniphila Supplementation

Targeted probiotic to support gut barrier integrity and mucosal health.

Akkermansia was not detected in your sample. Population average is 5.05%. Supplementation may significantly improve gut lining health.

Akkermansia muciniphila
ProbioticHigh

Saccharomyces boulardii

Beneficial yeast probiotic to support digestive resilience and pathogen defense.

Supports gut barrier function and helps maintain microbial balance during dietary changes.

SupplementHigh

Targeted Butyrate Support (Buty Caps)

Tributyrin supplementation (300-600mg/day) to support gut barrier function.

While butyrate producers are present, additional support strengthens the gut lining and anti-inflammatory pathways.

DietHigh

Increase Prebiotic Fiber Diversity

Aim for 30+ different plant foods per week. Focus on resistant starch and diverse fibers.

Your diversity is above average but several key species (Phocaeicola vulgatus, Roseburia CAG 303) are not detected. Diverse fiber can help recruit missing species.

DietMedium

Polyphenol-Rich Foods

Increase berries, dark chocolate, green tea, and colorful vegetables.

Polyphenols selectively feed beneficial bacteria and have direct anti-inflammatory effects.

DietMedium

Manage Oxalate Intake

Reduce high-oxalate foods (spinach, rhubarb, almonds) and pair with calcium-rich foods.

Your oxalate metabolism pathway is rated Low, suggesting limited capacity to break down dietary oxalates.

LifestyleMedium

Circadian Rhythm Optimization

Consistent sleep/wake times, morning sunlight exposure, evening wind-down routine.

Supports the gut-brain axis and helps maintain healthy microbial rhythms.

SupplementLow

Omega-3 Fatty Acids

EPA/DHA supplementation (2g/day) to support anti-inflammatory pathways.

Helps manage the moderate inflammatory potential detected in your profile.

Compare to Previous

Track your microbiome health journey over time

Previous:Nov 15, 2025
Current:Feb 17, 2026
(94 days)
Overall Improvement Detected
Your microbiome health has improved since your last test. Keep up the great work!
Brilliant Score+7 pts
7568
Shannon Index+0.7
5.54.8
Biological Age-2 yrs
5860(actual: 63)
Health Category Comparison
Microbiome Diversity
Great(+23)
Inflammatory Potential
Average
Metabolic Fitness
Great(+17)
SCFA Production
Great(+17)
Gut Lining Health
Great(+40)
Oxalate Metabolism
Needs Improvement
Gas Production Pathways
Average
Ammonia Pathways
Average
Salt Pathways
Needs Improvement
Bile Acid Pathways
Average
TMA Production Pathways
Needs Improvement
Antibiotic Resistance
Absent
Current
Previous

Methodology

This report was generated using shotgun metagenomic sequencing of your stool sample. DNA was extracted and sequenced using Illumina NovaSeq 6000 platform with paired-end 150bp reads.

Taxonomic classification was performed using a proprietary database of over 120,000 reference genomes. Functional pathway analysis utilized HUMAnN 3.0 with UniRef90 and MetaCyc databases.

Health scores are calculated using proprietary algorithms that integrate abundance data, functional pathway activity, and published clinical associations from over 50,000 peer-reviewed studies.

Important Notice

This report is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Results should be interpreted in consultation with a qualified healthcare provider.

Microbiome composition is dynamic and can change with diet, lifestyle, medications, and other factors. We recommend retesting every 3-6 months to track progress.

Report ID: RPT-FF05465495-2026-02-17 | Version 2.1 | CLIA #99D2064315