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Microbiome Intelligence Report

Mary Ann Melkonian

Sample Date: Feb 10, 2026 · Report: Feb 17, 2026

ID: FF05465495 · Kit: KIT-BB-20260210-5495 · Stool Sample

Physician: Dr. Sierra Simpson, MD

75/ 100
Brilliant Score
+7 pts
vs previous
Shannon Index
5.5
Simpson: 0.95
Biological Age
58
5 years younger
Species Detected
312
248 pathways
F:B Ratio
0.98
Firmicutes:Bacteroidetes

Your Personalized Summary

AI-generated analysis of your microbiome profile

Hello Mary Ann, it's wonderful to review your latest microbiome results! We're thrilled to see significant progress since your last test, reflecting your dedication to your gut health journey. Your Brilliant Score has climbed from 68 to an impressive 75, indicating a robust and thriving internal ecosystem. Even more exciting, your biological age is now estimated at 58, which is 5 years younger than your chronological age and a 2-year improvement from your previous test! This suggests your gut is supporting your overall vitality beautifully. You have a rich and diverse community of beneficial bacteria, including excellent levels of key players like Phocaeicola dorei and Bifidobacterium longum, which are crucial for fiber digestion and immune support. While your microbiome is performing exceptionally well in many areas, we've identified a few opportunities for further optimization, such as addressing moderate inflammation and supporting oxalate metabolism. We're confident that with continued focus, you can build on this fantastic foundation to achieve even greater gut health.

Your Gut Health Wins

Here's what your microbiome is doing right

5 Years Younger Biologically

Your gut microbiome suggests a biological age of 58, which is 5 years younger than your actual age. This is associated with better metabolic health and longevity.

Exceptional Microbial Diversity

Your Shannon Index of 5.5 puts you in the top quartile. A diverse microbiome is more resilient — like a well-diversified portfolio for your health.

312 Species Detected

Your gut is home to 312 distinct species — a rich ecosystem linked to better nutrient absorption and immune regulation.

3 Categories Rated "High"

Your Metabolic Fitness, SCFA Production, Gut Lining Health scored at the highest level — keep doing what you're doing.

Zero Pathogens Detected

Your sample tested negative for all screened pathogens, parasites, and viruses. Your gut's defense systems are functioning well.

8 Key Beneficial Species Thriving

Your gut is dominated by beneficial organisms that produce short-chain fatty acids and support your immune system — the MVPs of your microbiome.

+7 Point Improvement

Your Brilliant Score improved from 68 to 75 since your last test. Your interventions are making a real difference.

Health Categories

12 key dimensions of your gut health, each scored from your microbiome analysis

Microbiome Diversity

up
Above Average

Shannon index 5.5, Simpson 0.95 — your microbial ecosystem is rich and well-balanced.

Inflammatory Potential

stable
Average

Moderate inflammatory markers. Bilophila wadsworthia and Ruminococcus gnavus present at low levels.

Metabolic Fitness

up
High

Strong SCFA production and carbohydrate metabolism driven by multiple butyrate producers.

SCFA Production

stable
High

Excellent short-chain fatty acid production from Faecalibacterium, Anaerostipes, and Anaerobutyricum.

Gut Lining Health

up
High

Strong gut barrier integrity supported by butyrate producers and mucosal layer maintenance.

Oxalate Metabolism

stable
Low

Limited oxalate-degrading capacity detected. May benefit from dietary oxalate management.

Gas Production Pathways

stable
Average

Normal gas production levels. No significant methane or hydrogen sulfide overproduction.

Ammonia Pathways

stable
Average

Ammonia production within normal range. Adequate urea cycle support from gut microbes.

Salt Pathways

down
Low

Below average salt metabolism pathways. Consider monitoring sodium intake.

Bile Acid Pathways

stable
Average

Normal bile acid metabolism supporting fat digestion and cholesterol regulation.

TMA Production Pathways

stable
Low

Low TMA production is favorable — reduces cardiovascular risk from TMAO.

Antibiotic Resistance

stable
Not Detected

No antibiotic resistance genes detected in your sample.

Your Strengths

6 areas performing well

Microbiome DiversityAbove Average
Metabolic FitnessHigh
SCFA ProductionHigh
Gut Lining HealthHigh
TMA Production PathwaysLow
Antibiotic ResistanceNot Detected

Areas to Watch

2 areas need attention

Oxalate MetabolismLow

Limited oxalate-degrading capacity detected. May benefit from dietary oxalate management.

Salt PathwaysLow

Below average salt metabolism pathways. Consider monitoring sodium intake.

Microbial Composition

Phylum-level breakdown of your gut microbiome

ECOSYSTEM312species detected
Bacteroidota41.06%
Ref: 30-50%
Bacillota40.07%
Ref: 30-55%
Verrucomicrobiota3.89%
Ref: 1-5%
Actinomycetota3.15%
Ref: 3-15%
Pseudomonadota0.76%
Ref: <5%
Thermodesulfobacteriota0.42%
Ref: <2%
Other0.65%
Ref: <5%
F:B

Firmicutes:Bacteroidetes Ratio

0.98 (optimal: 0.8-1.2)

Optimal

Key Species Identified

8 significant organisms detected in your sample

SpeciesAbundanceStatus
Phocaeicola dorei
85 publications
14.33%
Beneficial
Bacteroides ovatus
150 publications
12%
Beneficial
Bifidobacterium longum
420 publications
4.99%
Beneficial
Faecalibacterium prausnitzii
334 publications
3.92%
Beneficial
Lachnospira eligens
65 publications
3.91%
Beneficial
Anaerostipes hadrus
45 publications
2.75%
Beneficial
Anaerobutyricum hallii
38 publications
1.41%
Beneficial
Faecalibacterium longum
28 publications
3.13%
Beneficial

Dysbiotic Species

Organisms that may negatively impact your gut health

Bilophila wadsworthia0.47%

Bile-tolerant organism associated with higher-fat dietary patterns. Can increase hydrogen sulfide activity which may irritate the gut lining.

[Ruminococcus] gnavus0.38%

Mucin-adapted species that can contribute to mucus barrier thinning and immune activation in inflammation-prone environments.

Eggerthella lenta0.23%

Opportunistic pathobiont linked to inflammatory metabolic shifts and altered bile acid handling.

Bacteroides fragilis0.07%

While often a normal commensal, certain strains have pathogenic potential during dysbiosis.

Escherichia coli0.01%

Present at low abundance but clinically relevant because it can rapidly expand after antibiotics or dietary disruption.

Population Comparison

How your key species compare to the general population average

Faecalibacterium prausnitziiNeeds Improvement
You
3.92%
Average
7.35%
Phocaeicola vulgatusNeeds Improvement
You
N/D
Average
5.55%
Roseburia CAG 303Needs Improvement
You
N/D
Average
0.061%
Faecalibacterium duncaniaeNeeds Improvement
You
N/D
Average
3.94%
Lachnospira eligensHealthy
You
3.91%
Average
1.065%
Akkermansia muciniphilaNeeds Improvement
You
N/D
Average
5.05%

Functional Pathways

10 metabolic pathways analyzed from your microbiome

Butyrate ProductionSCFA Metabolism
Active82

Gut barrier integrity, anti-inflammatory

Propionate SynthesisSCFA Metabolism
Active71

Appetite regulation, gluconeogenesis

Acetate ProductionSCFA Metabolism
Active88

Energy source, cross-feeding substrate

Vitamin B12 SynthesisVitamin Metabolism
Active55

Energy metabolism, neurological function

Folate BiosynthesisVitamin Metabolism
Active68

DNA synthesis, cell division

Tryptophan MetabolismAmino Acid Metabolism
Reduced48

Serotonin/melatonin precursor

GABA ProductionNeurotransmitter
Reduced42

Anxiety regulation, sleep quality

Bile Acid MetabolismLipid Metabolism
Active65

Fat digestion, cholesterol regulation

LPS BiosynthesisImmune Modulation
Reduced35

Low levels favorable — less immune activation

Oxalate DegradationMineral Metabolism
Depleted22

Kidney stone prevention

Functional Markers

Key biomarkers indicating digestive and immune function

Calprotectin

Moderate

Intestinal inflammation marker

Elastase-1

Moderate to High

Pancreatic function indicator

Secretory IgA

Moderate to High

Mucosal immune defense

Steatocrit

Low to Moderate

Fat malabsorption indicator

β-glucuronidase

Moderate to High

Estrogen metabolism, toxin recirculation

Zonulin

Moderate

Intestinal permeability (leaky gut) marker

Pathogen Screening

Comprehensive screening for harmful organisms

All Clear — No Pathogens Detected
26 organisms screened across 5 categories. Your gut ecosystem is clean.

Bacterial Pathogens

7 tested
Campylobacter spp.Clear
Clostridioides difficileClear
Enterotoxigenic E. coliClear
Salmonella spp.Clear
Shiga-toxin producing E. coliClear
Shigella / EIECClear
Yersinia enterocoliticaClear

Opportunistic/Overgrowth

7 tested
Citrobacter freundii/spp.Clear
Clostridioides difficile toxinsClear
Fusobacterium spp.Clear
Klebsiella pneumoniaeClear
Morganella morganiiClear
Proteus mirabilisClear
Pseudomonas aeruginosaClear

Parasites

4 tested
Cestode (Tapeworm) — 6 typesClear
Nematode (Roundworm) — 15 typesClear
Protozoa — 16 typesClear
Trematode (Fluke) — 7 typesClear

Viral Pathogens

5 tested
Adenovirus F40/41Clear
AstrovirusClear
Norovirus GI/GIIClear
Rotavirus AClear
SapovirusClear

Fungal/Yeast

3 tested
Candida albicansClear
Candida spp. (non-albicans)Clear
Geotrichum spp.Clear

Symptom Connections

How your microbiome may be influencing symptoms

Digestive
Occasional Bloating
Immune
Moderate Immune Activation
Metabolic
Oxalate Sensitivity
Gut-Brain
Mild Gut-Brain Axis Imbalance

Personalized Recommendations

8 targeted actions based on your unique microbiome profile

ProbioticHigh

Akkermansia muciniphila Supplementation

Targeted probiotic to support gut barrier integrity and mucosal health.

Akkermansia was not detected in your sample. Population average is 5.05%. Supplementation may significantly improve gut lining health.

Akkermansia muciniphila
ProbioticHigh

Saccharomyces boulardii

Beneficial yeast probiotic to support digestive resilience and pathogen defense.

Supports gut barrier function and helps maintain microbial balance during dietary changes.

SupplementHigh

Targeted Butyrate Support (Buty Caps)

Tributyrin supplementation (300-600mg/day) to support gut barrier function.

While butyrate producers are present, additional support strengthens the gut lining and anti-inflammatory pathways.

DietHigh

Increase Prebiotic Fiber Diversity

Aim for 30+ different plant foods per week. Focus on resistant starch and diverse fibers.

Your diversity is above average but several key species (Phocaeicola vulgatus, Roseburia CAG 303) are not detected. Diverse fiber can help recruit missing species.

DietMedium

Polyphenol-Rich Foods

Increase berries, dark chocolate, green tea, and colorful vegetables.

Polyphenols selectively feed beneficial bacteria and have direct anti-inflammatory effects.

DietMedium

Manage Oxalate Intake

Reduce high-oxalate foods (spinach, rhubarb, almonds) and pair with calcium-rich foods.

Your oxalate metabolism pathway is rated Low, suggesting limited capacity to break down dietary oxalates.

LifestyleMedium

Circadian Rhythm Optimization

Consistent sleep/wake times, morning sunlight exposure, evening wind-down routine.

Supports the gut-brain axis and helps maintain healthy microbial rhythms.

SupplementLow

Omega-3 Fatty Acids

EPA/DHA supplementation (2g/day) to support anti-inflammatory pathways.

Helps manage the moderate inflammatory potential detected in your profile.

Species Abundance Changes

Track how your key species have changed over time

Time Range
Showing data from 6 months before current report
Phocaeicola doreiBeneficial
14.3%
+1.5%
Bacteroides ovatusBeneficial
12.0%
+1.2%
Bifidobacterium longumBeneficial
5.0%
+0.9%
Faecalibacterium prausnitziiBeneficial
3.9%
+0.5%
Anaerostipes hadrusBeneficial
2.8%
+0.5%
Lachnospira eligensBeneficial
3.9%
+0.4%
Bilophila wadsworthiaOpportunistic
0.5%
-0.2%
Escherichia coliOpportunistic
0.0%
-0.0%
6 increasing
2 decreasing
0 stable

Methodology & Disclaimer

This report is generated from metagenomic sequencing of your stool sample using shotgun whole-genome sequencing (WGS) technology. Taxonomic classification is performed using the MetaPhlAn4 pipeline against the ChocoPhlAn database. Functional pathway analysis uses HUMAnN3 with UniRef90 clustering. All results are compared against a reference population of 10,000+ healthy adults.

Sample quality was assessed as Excellent with adequate DNA yield for reliable analysis. The Brilliant Score is a proprietary composite metric incorporating diversity, beneficial species abundance, pathogen absence, and functional pathway activity.

Disclaimer: This report is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare provider before making changes to your diet, supplement regimen, or medical treatment plan.